• Unifarm, Viale Andrea Doria 21, 95125 Catania
  • +39 095 7167514
  • +39 095 2865220
  • info@unifarm.org

The bioanalytical laboratory of UNIFARM is certified by the Azienda Sanitaria Provinciale of Catania according to D.M 19/03/1998 and is included in the Registry of private laboratories of the OsSC.

The laboratory performs bioanalyses of biological materials (blood, plasma, serum, urine, tissue and others) according to GLP (Good Laboratory Practice).

The skill and technical-scientific expertise of its staff, as well as  the high level of equipment available allow UNIFARM to have an advanced laboratory able to develop validated analytical methods according to international guidelines.

In particular the laboratory is able to:

- develop and validate analytical methods;

 determine active ingredients and metabolites in pharmacokinetic and pharmacodynamic studies;

- determine marker levels in bioequivalence and bioavailability studies;

- prepare validation reports;

- prepare analytical reports;

- prepare SOPs.

The main analytical equipments are:

- HPLC/DAD (Varian);

- HPLC/ECD (ESA); 

- HPLC/MS/MS (Agilent). 

Examples of bioanalytical validation methods

Composti

Matrice

Metodo

9-Idroxy-risperidone

plasma

LC-MS/MS

Acetyl-L-carnitine

plasma

LC-MS/MS

Daidzein

siero

HPLC/ECD

Desketoprofene

plasma

LC-MS/MS

Dexamethasone

plasma

LC-MS/MS

Frovatriptan

plasma

LC-MS/MS

Diclofenac

plasma

LC-MS/MS

Eperisone

plasma

LC-MS/MS

Escitalopram

plasma

LC-MS/MS

Fluvastatin

plasma

LC-MS/MS

Genistein

siero

HPLC/ECD

L-carnitine

plasma

LC-MS/MS

Olanzapine

plasma

LC-MS/MS

Propyonil-L-carnitine

plasma

LC-MS/MS

Riluzole

plasma

LC-MS/MS

Risperidone

plasma

LC-MS/MS

Simvastatin

plasma

LC-MS/MS

Simvastatin-β-hydroxyacid

plasma

LC-MS/MS

Thiocolchicoside

siero

HPLC/ECD

Triazolam

plasma

HPLC/UV